Prescreening Membrane Protein Crystallization Conditions with FRAP

April 28, 2017 by Lance Ramsey Leave a Comment

Authors: Lance Ramsey, Ellen Gualtieri, Eric Zhao

[Read more…]

Posted in: Protein Crystallization, FRAP, lcp, prescreening conditions, membrane proteins, protein crystals

Multi-Fluorescence Imaging of Protein Crystals

April 24, 2017 by Lance Ramsey Leave a Comment
[Read more…]

Posted in: Protein Crystallization, imaging, protein-protein complexes, membrane proteins, protein crystals

Unprecedented Sensitivity for API Crystalline Quantification using SONICC

April 14, 2017 by Lance Ramsey Leave a Comment

SONICC (Second Order Nonlinear Imaging of Chiral Crystals) is a novel imaging technique that offers unprecedented sensitivity in quantifying small molecule crystallinity. SONICC can be used to detect concentrations of crystalline APIs down to...

[Read more…]

Posted in: SONICC, Amorphous solid dispersions, api, crystallinity, chiral crystals, Active Pharmaceutical Ingredients

Active Pharmaceutical Ingredient Characterization using SONICC

April 12, 2017 by Lance Ramsey Leave a Comment

SONICC (Second Order Nonlinear Imaging of Chiral Crystals) uses a femtosecond pulsed laser to exploit the frequency-doubling effect produced by the majority of Active Pharmaceutical Ingredients (APIs) and allows for 2-orders of magnitude...

[Read more…]

Posted in: SONICC, Amorphous solid dispersions, Active Pharmaceutical Ingredients

Cold Spring Harbor Asia - Membrane Proteins: Structure & Function

April 10, 2017 by Lance Ramsey Leave a Comment
[Read more…]

Posted in: Protein Crystallization, Rock Maker, NT8, Rock Imager, SONICC, FRAP, lipidic cubic phase, lcp, mfi, membrane proteins

Detection and Imaging of Protein Microcrystals using SONICC

April 06, 2017 by Lance Ramsey Leave a Comment

Authors: Ellen Gualtieri, Eric Zhao, Lance RamseyAbout SONICCSONICC, Second Order Non-linear Imaging of Chiral Crystals, uses a femtosecond pulsed laser to exploit the frequency-doubling effect found in the majority of protein crystals, and...

[Read more…]

Posted in: Protein Crystallization, SONICC, imaging, lcp, membrane proteins, protein crystals

British Crystallographic Association Spring Meeting 2017

April 04, 2017 by Lance Ramsey Leave a Comment
[Read more…]

Posted in: Protein Crystallization, Rock Maker, NT8, Rock Imager, SONICC, mfi

Subscribe to Email Updates