Unprecedented Sensitivity for API Crystalline Quantification using SONICC

April 14, 2017 by Lance Ramsey Leave a Comment

SONICC (Second Order Nonlinear Imaging of Chiral Crystals) is a novel imaging technique that offers unprecedented sensitivity in quantifying small molecule crystallinity. SONICC can be used to detect concentrations of crystalline APIs down to...

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Posted in: SONICC, Amorphous solid dispersions, api, crystallinity, chiral crystals, Active Pharmaceutical Ingredients

Active Pharmaceutical Ingredient Characterization using SONICC

April 12, 2017 by Lance Ramsey Leave a Comment

SONICC (Second Order Nonlinear Imaging of Chiral Crystals) uses a femtosecond pulsed laser to exploit the frequency-doubling effect produced by the majority of Active Pharmaceutical Ingredients (APIs) and allows for 2-orders of magnitude...

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Posted in: SONICC, Amorphous solid dispersions, Active Pharmaceutical Ingredients

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